The most feared duet
Since me and Elton, played career Russian Roulette

from Eminem – Business Lyrics on Rap Genius

Meaning

Eminem was under fire for homophobic lyrics, so he performed “Stan” with Elton John at the Grammy’s despite the protests from the homosexual community. If this went badly it could have ruined both of them. Eminem could have been accused of using Elton just to shake off the GLAD, which could have further sunk his career. And Elton could have alienated his gay fans just for associating with the alleged homophobe Eminem. Luckily it went fairly well, it helped satisfy some critics that Eminem wasn’t truly against gays, and Elton was no worse off because of it.

http://www.youtube.com/watch?v=ZY2p7oE7Bpw

Russian Roulette refers to the game where you load one bullet in a revolver, spin the cylinder, and then pull the trigger to your head. The point here is that it’s a huge risk that can potentially end you, which is what these two were going through then. And then he uses this emotion of fear to describe how other rappers feel when they see him and Dre together.

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