Ain't nobody fucking with my
Clique, clique, clique, clique, clique
Ain't nobody fresher than my muthafuckin
Clique, clique, clique, clique, clique

from Kanye West (Ft. Big Sean & Jay Z) – Clique Lyrics on Rap Genius

Meaning

clique [kleek, klik] n.: exclusive group; a close group of friends or coworkers with similar interests and goals, whom outsiders regard as excluding them.

Nobody does it as well as Sean’s clique (AKA music label), G.O.O.D. Music, which includes superstar artists like Kanye West, Kid Cudi, Common, John Legend, Pusha T, D'Banj and Big Sean himself.

When Sean repeats “clique” it also represents the paparazzi’s cameras clicking when the G.O.O.D. crew walks by.

It could also refer to the G.O.O.D. crew threateningly cocking their guns in preparation for a battle from any of their naysayers. Like this:
http://www.youtube.com/watch?v=8xTqP58o1iw

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