I could tell you what a dope boy feels like
I could tell you that he never sleeps
He may smile but it's never sweet

from Rick Ross (Ft. Omarion) – Ice Cold Lyrics on Rap Genius

Meaning

A “Dope Boy” Is out getting that money so there’s no time to sleep because there’s always someone one step ahead of you and you gotta catch em. They always on guard and on alert and not alot of people to trust so there is really not alot to smile about.

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