I hit the green just to maintain, feelin pain
For all the niggas that I lost to the game... from my block

from 2Pac – My Block (Remix) Lyrics on Rap Genius

Meaning

Now 2Pac needs marijuana to put him in a numb-state because the pain and the stress is too much for him to handle. He says he feels pain to all of his homies that passed away because of the danger that living such a life leads to.

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