Pickin' stems out the piccolo, tickle your brain ventricles

from Jean Grae (Ft. Ab-Soul, Sarkodie & Talib Kweli) – BET Cypher 2012: The True School Lyrics on Rap Genius

Meaning

Piccolo was the mainly green main character in the Dragon Ball/Z/GT series, in this case, piccolo means weed so strong, it effects the ventricles of your brain.

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