You only live once, you only live once
Watch Rick Ross give his Jesus piece to a bum

from Macklemore and Ryan Lewis – Gold Lyrics on Rap Genius

Meaning

Rick Ross is known for his lavish jewelry and likes to brag about it.
He also likes to associate himself with the phrase YOLO.

Macklemore flips this on him and hopes Rosay will live up to the motto and use the limited time allotted to us, by doing some good for humanity.

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