If Pirus and Crips all got along
They'd probably gun me down by the end of this song

from Kendrick Lamar (Ft. MC Eiht) – M.A.A.d City Lyrics on Rap Genius


Piru Bloods and Compton Crips are enemies. He’s giving the listener a warning that by the end of the song both gangs will come together against a common enemy: him. He raps against their lifestyle and influences, which wouldn’t make them very happy.

Kendrick also may be saying that because he is talking down on their way of life they might join together to get him.

He also mentions them in the hook of “Ronald Reagan Era” on Section.80:

Compton Crip niggas ain’t nothin' to fuck with
Bompton Pirus ain’t nothin' to fuck with
Compton éses ain’t nothin' to fuck with
But they fuck with me, and bitch I love it

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