I would've washed a pill down with a shot of my own spinal fluid
from Slaughterhouse (Ft. Skylar Grey) – Rescue Me Lyrics 1 on Rap Genius
Meaning
Ecstasy pills affect one’s spinal fluid (and spinal fluid is final, you won’t get it back). Washing his pill with that fluid depicts the reckless risks he was darkness-sunk enough to take at the time.
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