One day he goes and take a glimpse in the mirror
But he doesn't recognize his own face
His health is fading and he doesn't know why

from TLC – Waterfalls Lyrics on Rap Genius

Meaning

The consequences of his reckless love made it so that his body could not handle traces of the STD (and most likely HIV). The marks are showing on his face, from spots to a general pale tone. Without his knowledge, HIV is destroying him.

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