Responsible for how the wasted youth is
This line contains metonymy and some clever wordplay.
The drug epidemic is responsible for the social problems which make young people do the antisocial things described in the next few lines. Rather than directly say this, El takes the typical drug addict he just described as representing the whole drug epidemic. This is an example of metonymy.
Young people’s lives are “wasted” because they’re doing antisocial things, but since they’re “popping pills”, they are also “wasted” because they are literally high.
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