I have ya in the morning like a dope fiend sick

from 50 Cent – Gangsta's Delight Lyrics on Rap Genius

Meaning

Continuing on the drug/sex references, 50 will have you feeling sick in the morning from your “ultimate trip”.

The dope he is referring to is cocaine. If you have too much (which an addict would) it will give you a serious hangover the next morning, just how this woman will feel like after 50 just spent the night with her.

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