Multiple orgasms, that’s my M.O

from Game (Ft. Big Sean, Fabolous, Jeremih & Lil Wayne) – All That (Lady) Lyrics on Rap Genius

Meaning

M.O. = Multiple orgasms

M.O also stands for Modus Operandi, meaning how one does things. Therefore Wayne is saying his style is always giving ladies multiple orgasms.

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