That's GBE, when them two-two-threes get to flyin' bitch its over

from Chief Keef (Ft. 50 Cent & Wiz Khalifa) – Hate Bein' Sober Lyrics 1 on Rap Genius

Meaning

.223 sporting ammo are usually used in M16 rifles. These guns are extremely accurate and powerful, so if 50 takes one out, you better start running!

Different Types of M16’s:

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