Dominick feels, like he’s vomiting pills, throwing E’s up

from DJ Drama (Ft. B.o.B & Crooked I) – Take My City Lyrics on Rap Genius

Meaning

Wordplay on throwing up the eastside (see next line) and vomiting ecstacy pills, because Dominick Wickliffe (Crooked I’s birthname) has been drinking and celebrating so much, that he got sick from the alchohol.

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