I smoke a blunt to take the pain out
And if I wasn't high, I'd probably try to blow my brains out

from 2Pac – Lord Knows Lyrics on Rap Genius

Meaning

*Pac’s last line before the chorus hits again is the same line he uses to begin the song…

This signifies that he relies on smoking weed a lot… in order to temporarily forget about the pain he’s going through…

Otherwise, he’d probably shoot himself in the head.

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