So they ask me - why you call it Late Registration 'Ye?
Cause we takin these muh'fuckers back to school

from Kanye West (Ft. Nas & Really Doe) – We Major Lyrics on Rap Genius

Meaning

They are taking them back to school, or schooling them, a common phrase when a someone skillfully beats someone in something.

Also: “Back to School” could be read as “Back to Basics”

Kanye is famous for reviving sampling in Hip-Hop, an old technique that Kanye made popular again with all of his albums. Late Registration itself was known for making older techniques from the Boom-Bap era of hip-hop relevant again.

To help improve the meaning of these lyrics, visit “We Major” by Kanye West (Ft. Nas & Really Doe) Lyrics and leave a comment on the lyrics box