Nigga had to cancel that bitch like Nino
In the movie New Jack City, main character Nino Brown orders his girlfriend’s murder with the phrase “cancel that bitch”. Wayne just means ending the relationship though
Also, The Nino Brown Story was an episode series that Lil Wayne was featured in. It was canceled, hence the phrase “cancel that bitch like Nino”.
To help improve the meaning of these lyrics, visit "Single" by Lil Wayne Lyrics and leave a comment on the lyrics box