Now it's on in the ghetto you ain't heard?
Niggas got they AK's headin' for the burbs
Aimin' at them skin headed bitches let it rain
Givin' 'em a wet, welcome to the house of pain

from The Notorious B.I.G. (Ft. 2Pac, Mary J. Blige & Nas) – Living In Pain Lyrics on Rap Genius

Meaning

Pac and his homies are taking revenge on skin head fucks from the suburbs

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