Niggas cut they nose off just to spite their face

from Gillie Da Kid (Ft. Pusha T) – Tryna Get Me One Lyrics on Rap Genius

Meaning

Usually when you’re addicted to drugs such as cocaine, you don’t necessarily appreciate yourself or your well being for that matter — hence, “spiting your face”.

With prolonged use of cocaine and other drugs you “snort”, it can damage the cartilage in your nose to such an extent that you literally look like your nose is cut off. If you’re interested, see this

So now note the wordplay — you hated yourself so you did cocaine, now you hate yourself even more because you have no nose!

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