I be pushing Niggas buttons like F2
And I'm the reason that your sweetheart left you
from Nacho Picasso – Surf Nazis Must Die Lyrics on Rap Genius
Meaning
Just like that thing on your keyboard, Nacho is pushing other guy’s buttons.
He claims that women will leave their men for him, no matter how much they claim to have “loved” them. Which is made apparent by the various women found in his presence in his various album covers:

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