Home was once an empty vacuum that's filled
Home had no substance, no essence. It was just a physical place that he had to give some a spot to run away to, which ended up being drugs. This could perhaps also be referencing the alienation from his family that he may have received after them finding out about his addiction.
To help improve the meaning of these lyrics, visit “Home Is Where The Hatred Is” by Gil Scott-Heron Lyrics and leave a comment on the lyrics box