I'm the illest mothafucka breathin', fuck yo rhyme or yo reason
Fucking over yo issues, it's kill-a-ho-nigga season

from Pusha T (Ft. Andrea Martin) – Take My Life Lyrics on Rap Genius

Meaning

Play on the idiom “rhyme and reason”, and an awesome shot at Drake.

Reference to “Illest Motherfucker Alive” from Watch the Throne. Push is stating he’s the shit and he couldn’t care less about your petty rhymes.

Furthermore, addressing Drake more directly:

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