Don't let me lose you, I'm not trying to confuse you
When I let loose with this Uzi and just shoot through your Isuzu
You get the message? Am I getting through to you?
You know what's coming, you motherfuckers don't even know, do you?

from 50 Cent (Ft. Eminem) – Patiently Waiting Lyrics on Rap Genius

Meaning

Here he’s incorporating a subtle diss into the line: you drive an Isuzu (not exactly balling)

This also is a reference to ‘’Gimme The Loot‘’ by The Notorious B.I.G. when him and his friend see people in an Isuzu and decide to rob and shoot through the car.

To help improve the meaning of these lyrics, visit “Patiently Waiting” by 50 Cent (Ft. Eminem) Lyrics and leave a comment on the lyrics box