Life's a bitch with a pretty face, but she burning

from 50 Cent – Ghetto Qu'ran (Forgive Me) Lyrics 1 on Rap Genius

Meaning

The hustling life is like a pretty woman with an STD — she may appear attractive, but she has hidden dangers

To “get burned” is to get an STD; “burning”, used to mean “spreading STDs” is a reversal of the standard phrase

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