And I knew you and your girl ain't speaking no more
Cause my dick all in her mouth
The classic hip-hop trope: “if that girl keeps fuckin' up, I’ll just fuck her friend”. Big Boi is clearly sick of dealing with his baby mama’s bullshit so he begins getting with her friends to piss her off. This causes the two of them to stop talking — first off, because you literally can’t talk with a penis inside your mouth, and secondly because the action of getting with this girl’s ex is unforgivable.
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