Picked you up when you was 9, started out my life of crime
With you, bought you some shells when you turned 22

from 2Pac – Me and My Girlfriend Lyrics on Rap Genius

Meaning

Another play on common gun calibers (9mm, .22LR). Tupac started out his love for guns with the simple yet fairly common 9mm handpistol. He then upgraded to a .22LR, complete with ammunition.

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