But I swear with these 50 shots, I'll shoot it out with 5-0
“5-0” refers to police officers.
Wayne is willing to have a shoot-out with police officers.
Weezy has expressed his disapproval for police officers before, more recently with the line
Numbers don’t lie
On his song titled “Get Smoked” off of his Dedication 4 mixtape
This is also a double entendre, Weezy F. will not only shoot it out with 5-0 as in police officers, but he will literally shoot it because 50 Shots Set’s it Off. “I’ll shoot it out with 5-0” also means he has 50 shots to shoot.
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