Cause no one knows and nobody got
Any out no N-O, that they better not

from Rich Boy (Ft. Lil Wayne & Nas) – Ghetto Rich Lyrics on Rap Genius

Meaning

Citizens have almost accepted the endless circle of violence. There is no way out of the N.O. (New Orleans)

If you’re looking for some good office bathroom reading, check out this long piece about gang violence in New Orleans

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