Life's a bitch and then you die
That's why we get high

from Nas (Ft. AZ) – Life's a Bitch Lyrics on Rap Genius

Meaning

Many look down on drug use, but AZ points out how for just about anyone, life is destined to be a bitch, regardless of how hard one works, and something like smoking weed helps ease the inevitable pain. Nas’s following verse has a little more hopeful tone in regards to this idea.

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