I can give you niggas something you can talk about
I can turn your smile upside down

from Lloyd Banks (Ft. 50 Cent, Eminem & Nate Dogg) – Warrior Pt.2 Lyrics on Rap Genius

Meaning

A smile upside down is a frown, an indication of displeasure.

Mess with Nate Dogg and you won’t end up smiling.

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