I've been hated by many, wanted by plenty
Disliked by some, but confronted by none
Since they don't show me sincerity, I load up, lock up
Take shots at em I guess you could call it a parody

from Drake (Ft. Nickelus F) – A Scorpio's Mind Lyrics on Rap Genius

Meaning

All four lines are metaphors about people who talk shit about you behind your back but refuse to tell you to your face,(confronted by none). And since they aren’t being real with him he will, ‘load up, lock up’, by getting dirt on them and “take shots” or diss on them. The last part about a parody is a metaphor explaining he won’t actually shoot and kill them, only kill their reputation.

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