I'm high as a bitch: up, up and away,

from Eminem (Ft. Lil Wayne) – No Love Lyrics on Rap Genius

Meaning

“Up, up and away” was once a phrase used in Superman comics.

“Up, up and Away” is also a 1960s song by The 5th Dimension

Weezy uses it to mean he’s high on drugs (this is probably what the O.G. song meant too; the hook is “would you like to riiide up in my ballooon?”)

This line made quite an impact on hip-hop. Weezy influenced himself to create his own song about this state of highness… and so did Kid Cudi.)

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