He does not mean to lesbians offend
But Lindsay: please come back to seeing men
Samantha's a 2; you're practically a 10

from Eminem – We Made You Lyrics on Rap Genius

Meaning

Reference to actress Lindsay Lohan’s lesbian love affair with Samantha Ronson

LESBIANS: don’t get pissed, but we want old “firecrotch” back on our team!

“Please come back to seeing men / semen”. It’s prounounced in the song as: SE-MEN …. It’s wordplay, please come back to sperm (males)

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