Cotton to silk, Motrin to Tylenol 3 pills

from Eminem – Microphone Freestyle Lyrics on Rap Genius

Meaning

He can spin cotton to silk just like the princess in Rumplestilskin could spin hay to gold, and he can do similar things to Motrin

Shady is sayin just like he can turn straw into gold and cotton to silk, he can turn moltrin into tylenol 3, tylenol 3 is a form of tylenol with codeine in it

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