El Gran Santo on the mantle
El Gran Santo(The Great Saint) is most likely referring to Santa Muerte, as many whom swear by her protection refer to her as the great saint or El Gran Santo.
Drug Traffickers have adopted this saint as the protector of the trade. Santa Muerte is typically worshiped in private and has caught a negative reputation because the only private shrines in the media are the one in the raided homes of drug traffickers.
As seen in Breaking Bad:
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