All I know is I'm wallowing, self-loathing and hollow
Bottoms up on the pill bottle, maybe I'll hit my bottom tomorrow

from Eminem (Ft. Kobe) – Talkin' 2 Myself Lyrics on Rap Genius

Meaning

Em had a massive prescription drug problem that almost consumed him. He wasn’t necessarily waiting for it to kill him, but for it to get bad enough to get his shit together.

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