Taking over the world no Pinky just a lotta Brain

from Drake (Ft. Mickey Factz & Travie McCoy) – Overdose Lyrics on Rap Genius

Meaning

“Pinky and The Brain” is an old cartoon from 2001 that featured 2 mice. Brain made plots for world domination (as Drake tries to “kill everything” with his rap) and Pinky is simply his brainless companion. Drake is taking over the world in whatever way possible. He does not need to hold up his pinky like a classy person when they drink tea.

Also, he is saying he gets a lot of head or “brain”

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