I'm in the basement mixin' up the medicine – cocaine and heroin

from Shabaam Sahdeeq (Ft. 151 Proof, Bekay, Climax, Dov, El Gant, FaMo$o, Flo, F.T. & Nutso) – Southpaw Cypher Lyrics on Rap Genius

Meaning

Reference to the Bob Dylan track “Subterranean Homesick Blues,” which crotchety old white dudes insist is “the first rap song ever.” More recently, Juelz Santana mixed up his own medicine

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