I smoke a blunt to take the pain out

from 2Pac – Lord Knows Lyrics on Rap Genius

Meaning

Tupac was heavily into weed while around the time he was recording “Me Against The World” because he was paronoid (which he said in Tupac Resurrection).
Topic starts at 1:09:27

https://www.youtube.com/watch?v=GkQrQuqoKs0

Smoking weed help erase the mind from all the bullshit life has to offer.

To help improve the meaning of these lyrics, visit “Lord Knows” by 2Pac Lyrics and leave a comment on the lyrics box