You niggas is featherweights, I'm Aftermath's heavyweight
Now Dre's weapon of mass destruction is 'bout to detonate

from Game (Ft. Kendrick Lamar) – The City Lyrics on Rap Genius

Meaning

Game is signed to Aftermath Records, founded by Dr. Dre in the wake of his split with Death Row. Game is proclaiming his superiority over nearly every other rapper with this line.

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