I am on my “mmhmm,” they are on they “Oh, No!”
This is Lupe saying he is being proactive and doing what he wants (especially considering his label’s unwanted push for him to do more radio friendly records, which could relate to the Oh, No! as in Oh, no! he’s not listening to us). Also, the Oh, No! is others willingness to do things they don’t agree with to get paid (hence, them not being “real” in the next line. Oh, No! could also be a statement regarding about fear of chasing your dreams.
To help improve the meaning of these lyrics, visit "All the Way Turnt Up" by Lupe Fiasco Lyrics and leave a comment on the lyrics box