Fucking with B.I.G. it ain't safe
A play on from “the lyrical molesting” line, meaning that he’ll murder you on track. Also molesting means to force someone to do something sexually, usually by force. In other words, if you mess with Biggie, he’s going to rape you lyrically, and he’s not going to go soft nor will he use protection. You are putting yourself in danger screwing around with Biggie. Simple enough.
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