Hustlin with the birds, known to take it off your shoulder

from Birdman (Ft. Lil Wayne) – I Run This Lyrics on Rap Genius

The first part refers to kilos of coke. I’m actually not sure if the second has a concrete definition, but by my way of thinking it is either a reference to “brushing one’s shoulders off” or readying a rifle or other long firearm.
It could also be that he’s claiming to cut peoples' heads off.

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