And pop E pills, yeah, call 'em X-Clan
So I tell 'em, "Vanglorious"

from Jim Jones (Ft. Cam'ron) – Toast Freestyle (Runaway Remix/Kanye Diss) Lyrics on Rap Genius

Meaning

Cam is punning on the name of the drug Ecstasy, commonly known as “E” or “X”, and the name of 1990’s Afrocentric rappers X-Clan, whose members used the (made up) word vanglorious as a trademark

“Vainglorious” is an SAT word meaning “cocky” — so I think of “Vanglorious” as an adjective describing Vans-wearing skater dudes who think they’re too cool

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