[Hook]
Who run the world? Girls! [x4]
Who run this motha? Girls! [x4]
Who run the world? Girls! [x4]

from Beyoncé (Ft. Jay Z, Lil Wayne & T.I.) – Run the World (Girls) Lyrics on Rap Genius

Meaning

It’s a rhetorical question. Beyoncé knows exactly who runs the [mothafucking] world — and apparently it’s girls.

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