And I ain't left this little room, trying to concentrate to breathe

from The Weeknd – Initiation Lyrics on Rap Genius

So much weed has been smoked in the room that its hard to breathe without inhaling smoke and staying high. See Hotboxing

Opiates also cause breathing to be depressed, and you have to literally concentrate to breathe because it is voluntary. Furthermore, lean causes you to breathe weird, especially if you suffer from respiratory problems.

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