Hit 'em with the shotgun
Call that shit the stop button

from Lil Wayne – Oh Let's Do It Lyrics on Rap Genius

Meaning

Double Entendre:

1) Weezy literally shoots someone with a shotgun, giving his firearm another nickname: “The Stop Button”.
2) Lil Wayne gives a female a shotgun of some of the dankest weed in the world, putting them on their ass, or causing them to stop.

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