Lookie, how can 6 dicks be pussies

from Eminem (Ft. Strike) – B-Rabbit vs. Lyckety-Splyt Lyrics on Rap Genius

Meaning

Using science to his advantage in the wordplay, asking how in the world can 6 dicks (pricks/assholes) be such pussies (scared bitches).

(Note that the Free World all got sensitive and stood up when he directed this line to them.

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