So blame it on Mr. OVOXO
The reason why I'm breathing all the vanity I know

from Drake (Ft. Kendrick Lamar) – Buried Alive (Interlude) Lyrics on Rap Genius

Meaning

So blame it on Drake, he’s highlighting and talking about the emotional consequences of a life of vanity and the life of ‘the party’ that Kendrick Lamar also raps about.

Drake crew: OVO (Octobers Very Own)
The Weeknd crew: XO (Ecstasy Oxycodone)

The Weeknd and Drake are very close and combine their crew names to make OVOXO.

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