After needin that, I'm down wit O.P.P., yeah

from Ice Cube – When Will They Shoot? Lyrics on Rap Genius

Meaning

“Down wit' O.P.P.” was the chorus of the 1991 hit “O.P.P.” by Naughty By Nature. Here, O.P.P. stands for “Other People’s Pussy”, meaning sexual relations with a woman already involved with another man.

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